Inflammatory Rheumatic Disorders and Bone

作者: Irene E. M. Bultink , Marijn Vis , Irene E. van der Horst-Bruinsma , Willem F. Lems

DOI: 10.1007/S11926-012-0252-8

关键词:

摘要: Inflammatory joint diseases such as rheumatoid arthritis, well other rheumatic conditions, systemic lupus erythematosus (SLE) and ankylosing spondylitis, comprise a heterogeneous group of disorders that are all associated with extra-articular side effects, including bone loss fractures. The concept osteoimmunology is based on growing insights into the links between immune system bone. pathogenesis osteoporosis in these patients multifactorial. We have, more or less an example, described this extensively for SLE. High disease activity (inflammation) immobility common factors substantially increase fracture risk patients, top background on, among factors, age, body mass index, gender. Although no reduction has been shown intervention studies inflammatory diseases, we present treatment options might be useful clinicians who treating patients.

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