Management of Chronic Spontaneous Urticaria in Routine Clinical Practice Following the EAACI/GA(2)LEN/EDF/WAO Guidelines

摘要: Abstract Introduction Chronic spontaneous urticaria is a prevalent and difficult-to-treat condition that has very negative impact on patient quality of life. Objective To describe the epidemiological clinical characteristics patients presenting with chronic response to treatment administered according EAACI/GA(2)LEN/EDF/WAO consensus guideline. Material method Descriptive cross-sectional study all who consulted skin allergy unit in dermatology department tertiary hospital Spain between July 2011 2015. Results The included 100 urticaria; inducible was present 45% cases, angioedema 40%. On diagnosis, 53% were taking nonsteroidal anti-inflammatory drugs. All treated second generation H1-antihistamines, but standard dose sufficient only 18% cases. Higher doses (up 4 times dose) achieved control 74% studied. H1-antihistamines required angioedema, presence associated lack these drugs (OR, 6.1%; P  Conclusions Doses higher than are most cases achieve urticaria. Angioedema failure respond antihistamines. In refractory can be omalizumab or ciclosporin. Patients do not generally avoid use agents.