Long-term follow-up study on gastric adenoma and its relation to gastric protruded carcinoma

作者: Toshiaki Kamiya , Tetsuo Morishita , Hitoshi Asakura , Soichiro Miura , Yoshio Munakata

DOI: 10.1002/1097-0142(19821201)50:11<2496::AID-CNCR2820501140>3.0.CO;2-1

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摘要: A total of 191 gastric adenomas in 178 patients was studied macroscopically by endoscopy and histopathologically endoscopic biopsy. Among the lesions, 85 74 were followed-up for six months to 12 years. Gastric found be more frequent aged, with a rate 0.1% third decade but 3.7% ninth decade, on gastroscopic examination. cancers coexistent seen 14 cases (8%), male than female (sex ratio, 12:2). Only eight lesions (9%) revealed macroscopic changes. Four these showed reduction size, while other four enlargement. In 21 (25%), histologic changes observed. (5%) changed from moderate dysplasia (Group III) nondysplastic or intestinal metaplasia I), III IV, vice versa) without malignant transformation, nine (11%) Neither submucosal invasion nor lymph node metastasis found. These consisted carcinoma situ small foci exhibiting dysplasia, gradual transition severe cancer resected obtained polypectomy surgical resection. addition, increase tissue repeated findings suggest that underwent transformation through dysplasia.

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