Clinical management of infectious contact lens complications: from antibiotics to quorum-sensing inhibitors
作者： Alexander A Bialasiewicz , Katharina A Breidenbach , Volker Klauss , Rashid M Al-Saeidi , Radha Shenoy
DOI: 10.1586/EOP.10.74
关键词:
摘要: Although effective drugs have become available, improvements in the treatment of contact lens-associated microbial keratitis are required. Over last decade, outcome bacterial has improved owing to fluoroquinolones, leading a better control infection, earlier institution anti-inflammatory therapy and surgical intervention. The antimicrobial effectiveness some antibiotics may be increased by preservatives. Antibiotic resistance according serum standard limits not been found relevant for eye, with exception methicillin-resistant Staphylococcus aureus. Newer antifungals (voriconazole, itraconazole) being evaluated, but mainstay is liposomal amphotericin B econzole or natamycin. Therapy acanthamebic (biguanides combinations) microsporidial (fluoroquinolones) infections remains unchanged. New hydrophilic lens materials slow down formation biofilm. Antibiofilm research introduced substa...
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