Extensive development of vulnerable plaques as a pan-coronary process in patients with myocardial infarction: an angioscopic study

作者: Masanori Asakura , Yasunori Ueda , Osamu Yamaguchi , Takayoshi Adachi , Atsushi Hirayama

DOI: 10.1016/S0735-1097(01)01135-4

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摘要: Abstract OBJECTIVES To test our hypothesis that the development of vulnerable plaques is not limited to culprit lesions, but a pan-coronary process, we directly observed all three major coronary arteries by angioscopy and evaluated prevalence yellow in patients with myocardial infarction (MI). BACKGROUND Although pathologic studies have suggested disruption atheromatous plaque plays role acute MI, whole MI has been clarified. METHODS Thirty-two undergoing follow-up catheterization one month after onset were prospectively consecutively enrolled this study. The thrombus was successfully 20 (58 arteries, 21 lesions) angioscopy. diameter stenosis (DS) lesions maximal (maxDS) nonculprit segments angiographically measured for each artery. RESULTS DS maxDS 27 ± 17% 19 13%, respectively. Yellow detected (90%) 17 (81%) equally prevalent infarct-related non–infarct-related (3.7 1.6 vs. 3.4 1.8 plaques/artery). However, only (2%) CONCLUSIONS In are widely diseased multiple though nondisrupted plaques. Acute may represent process development.

参考文章(23)
K Mizuno, A Miyamoto, K Satomura, A Kurita, M Sakurada, S Yanagida, H Nakamura, T Arai, Angioscopic coronary macromorphology in patients with acute coronary disorders The Lancet. ,vol. 337, pp. 809- 812 ,(1991) , 10.1016/0140-6736(91)92514-3
R J Siegel, M Ariani, M C Fishbein, J S Chae, J C Park, G Maurer, J S Forrester, Histopathologic validation of angioscopy and intravascular ultrasound. Circulation. ,vol. 84, pp. 109- 117 ,(1991) , 10.1161/01.CIR.84.1.109
Sergio Waxman, Michael A. Sassower, Murray A. Mittleman, Stuart Zarich, Akira Miyamoto, Karen S. Manzo, James E. Muller, George S. Abela, Richard W. Nesto, Angioscopic Predictors of Early Adverse Outcome After Coronary Angioplasty in Patients With Unstable Angina and Non–Q-Wave Myocardial Infarction Circulation. ,vol. 93, pp. 2106- 2113 ,(1996) , 10.1161/01.CIR.93.12.2106
P. Constantinides, Plaque fissures in human coronary thrombosis Journal of Atherosclerosis Research. ,vol. 6, pp. 1- 17 ,(1966) , 10.1016/S0368-1319(66)80056-X
Mark E. Brezinski, Guillermo J. Tearney, Brett E. Bouma, Stephen A. Boppart, Michael R. Hee, Eric A. Swanson, James F. Southern, James G. Fujimoto, Imaging of coronary artery microstructure (in vitro) with optical coherence tomography American Journal of Cardiology. ,vol. 77, pp. 92- 93 ,(1996) , 10.1016/S0002-9149(97)89143-6
Sergio Waxman, Murray A Mittleman, Stuart W Zarich, Philip J Fitzpatrick, Stanley M Lewis, David E Leeman, Samuel J Shubrooks, John T Snyder, James E Muller, Richard W Nesto, Angioscopic Assessment of Coronary Lesions Underlying Thrombus American Journal of Cardiology. ,vol. 79, pp. 1106- 1109 ,(1997) , 10.1016/S0002-9149(97)00056-8
Didier Giroud, Jian M. Li, Philip Urban, Bernhard Meier, Wilhelm Rutishauser, Relation of the site of acute myocardial infarction to the most severe coronary arterial stenosis at prior angiography American Journal of Cardiology. ,vol. 69, pp. 729- 732 ,(1992) , 10.1016/0002-9149(92)90495-K
Yasunori Ueda, Shinsuke Nanto, Kazuo Komamura, Kazuhisa Kodama, Neointimal coverage of stents in human coronary arteries observed by angioscopy Journal of the American College of Cardiology. ,vol. 23, pp. 341- 346 ,(1994) , 10.1016/0735-1097(94)90417-0
Yasunori Ueda, Masanori Asakura, Atsushi Hirayama, Kazuo Komamura, Masatsugu Hori, Kazuhisa Kodama, Intracoronary morphology of culprit lesions after reperfusion in acute myocardial infarction: Serial angioscopic observations Journal of the American College of Cardiology. ,vol. 27, pp. 606- 610 ,(1996) , 10.1016/0735-1097(95)00534-X