Paragangliome des Kopf-Hals-Bereiches - Tumorkontrolle, funktionelle Ergebnisse und Lebensqualität nach Operation

摘要: Background: Surgical therapy for paragangliomas (PG) of the head and neck is, due to alternatives radiation wait-and-scan strategy because postoperative morbidity, under ongoing discussion. Material Methods: Between 1981 2004, 79 patients with 94 PG were treated at our department. These had follow-up examination within a clinical trial considering tumor control, functional results first time neuropsychologically evaluated quality life. Mean was 65 months (1 228 months). Results: Among there 19 carotid body (GCP), 12 vagal nerve (GVP) 63 jugular-tympanal (JTP). Of these, 87 tumors underwent surgery. In 68 (78.1 %), could be removed completely. particular, complete resection GCP achieved in 100%, GVP 90.9 %, JTP type A B 83.3 C 66.6% D 61.5%. During period, residual or recurrent diagnosed 17 (19.5%). Six seven observed by magnetic resonance tomography did not show growth. One 6 recurrencies resected radiated 3 others are observation without showing growth tendencies. Two died postoperatively borderline operations extended tumors. The life after surgery showed SIP 4.8, which is comparably much better than acoustic neuroma (SIP 10.3). Conclusion: Whereas types almost ever possible cranial palsies, advanced causes often severe deficits. However, mostly good. Nevertheless, require an individualized therapeutic regime also including