Human skeletal muscle cytosols are refractory to cytochrome c-dependent activation of type-II caspases and lack APAF-1.

作者: David H Burgess , Michael Svensson , Tiziana Dandrea , Karina Grönlund , Folke Hammarquist

DOI: 10.1038/SJ.CDD.4400489

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摘要: … cytosol, subsequently activated by cytochrome c and dATP. In addition, we demonstratethatmusclecytosolslacktheapoptosisprotease activator protein-1 (APAF-1), both at … of …

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