Quality of life in advanced non-small cell lung cancer patients receiving palliative chemotherapy: a meta-analysis of randomized controlled trials

摘要: For advanced non-small cell lung cancer (NSCLC) patients, the only treatment option is palliative therapy, with aim of prolonging overall survival and improving disease-related symptoms quality life (QOL). However, to date, effect care on QOL has not yet been thoroughly examined, there no meta-analysis previous studies reporting outcomes following care. We consider that it important evaluate and/or response rates, but also in patients NSCLC receiving chemotherapy. The present study was obtain useful information for selection suitable chemotherapy regimens taking into consideration QOL, demonstrate importance assessments during treatment. performed a treatments compared carboplatin- cisplatin-based Trials were eligible analysis if they had who received prior chemotherapy, these reported data. In six trials analysis, 2,405 randomized receive or carboplatin-based higher global less severe than those rate, which primary outcome clinical trials, rate did differ significantly between two groups. It addition rates NSCLC, particularly when palliative.