Micronutrient levels and their effects on the prognosis of visceral leishmaniasis treatment, a prospective cohort study.

摘要: Micronutrients are minerals and vitamins they essential for normal physiological activities. The objectives of the study were to describe progress determinants micronutrient levels assess effects micronutrients in treatment outcome kalazar. A prospective cohort design was used. data collected using patient interviews, measuring anthropometric indicators, collecting laboratory samples. blood samples at five different periods during leishmaniasis treatments: before starting anti-leishmaniasis treatments, first week, second third 4th week treatments. Descriptive statistics used profile patients compare success rate. generalized estimating equation identify serum micronutrients. mean age 32.88 years [SD (standard deviation) ±15.95]. Male constitute 62.3% problematic alcohol use present 11.5% patients. zinc level visceral affected by (B − 2.7 [95% CI: − 4.01 - -1.5]), DDS (B 9.75 7.71–11.79]), family size -1.63 − 2.68 -0.58]), HIV -2.95 − 4.97 -0.92]), sex (B − 1.28 − 2.5 -0.07]). iron 7.6 5.86–9.35]), -5.14 − 7.01 -3.28]), malaria -12.69 − 14.53 -10.87]), Hookworm (− 4.48 [− 6.82 -2.14]), chronic diseases -7.44 − 9.75 -5.13]), -5.51 − 8.23 -2.78]). selenium -18.1 − 20.63 -15.58]) -11.36 − 13.02 -9.7]). iodine -38.02 − 41.98 -34.06]), 25 .84 22.57–29.1]), smoking -12.34 − 15.98 -8.7]), illness − 7.82 -2.46]), regular physical exercise 5.82 0.39–11.26]). vitamin D -9.43 − 10.92 -7.94]), 16.24 14.89–17.58]), -0.61 − 3.37 -3.37]), -1.15 − 2.03 -0.28]). residence 0.81 0.08–1.54]), BMI 1.52 0.42–2.6]), 1.62 0.36–2.88]), -5.03 − 5.83 -4.22]), -2.89 − 4.44 -1.34]),MUAC 0.86 0.52–1.21]), 0.09 0.07–0.12]). significantly lower. did not increase