Dietary Manipulation of Mouse Metabolism

作者: Jérôme N. Feige , Marie Lagouge , Johan Auwerx

DOI: 10.1002/0471142727.MB29B05S84

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摘要: The maintenance of metabolic homeostasis relies on the balanced intake nutrients from food. Consequently, diet composition strongly impacts whole-body physiology. Dietary formulations with strong nutrient imbalances can lead to disorders, lipids and simple sugars playing a prominent role. This unit describes how formulation be modified generate mouse models human pathologies, it details methodological procedures linked dietary manipulations, including caloric restriction introduction test compound

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