Composition of M-CSF conjugated to cytotoxic agents and a method for treating cancers characterized by over-expression of the c-fms proto-oncogene

作者: Eugene L. Brown

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摘要: A composition and method for treating cancers characterized by over-expression of the c-fms proto-oncogene/M-CSF receptor protein are provided. The involves a M-CSF polypeptide cross-linked to cytotoxic agent capable crossing into cytoplasm cell bearing killing cell.