Celiac plexus block increases quality of life in patients with pancreatic cancer.

摘要: Background Pancreatic cancer is a malignant disease with high mortality rate and severe pain that challenging to manage. To reduce the excruciating abdominal pain, opioids adjuvant agents are conventionally used. Objectives PRNCPB treatment of neural therapy. The number studies assessing effect on patients' QoL limited inconsistent. With this study, we intended address issue. Study design A prospective nonrandomized study series cases unresectable pancreatic was conducted. Setting performed at our clinic under real life conditions. Materials methods total 16 patients were enrolled in all whom had responded combined systemic analgesic therapy inadequately intolerable side effects contraindicating further increase dose. efficacy invasive, palliative procedure evaluated 35 days after performed. Primary outcomes changed intensity using VAS questionnaire. Secondary improved SF-36 Changes medications adverse reactions monitored. Results After experienced significant decrease (P=0.002) as shown by score, decreased opiate demand. Their scores considering sizes also (P<0.001). No complications attributable observed during period. Additionally, no drug observed. Limitations Detection, observation, reporting bias can be estimated moderate. Selection not detected. Conclusion Our results give preliminary evidence might helpful an additional conventional management end-stage patients. seems improve these time frame least 5 weeks intervention.