Cellular Signal Transduction and Nitric Oxide
作者： Stanley Heydrick
DOI: 10.1007/978-1-59259-002-5_3
关键词:
摘要: Nitric oxide (NO·) is an important regulatory determinant of vascular tissue homeostasis that evokes its functional effects through a broad range signaling elements, including the phospholipase C/calcium systems, tyrosine kinase pathways, G-proteinlinked receptors, ion channels, cyclic guanosine monophosphate (cGMP) and adenosine (cAMP)-dependent apoptotic pathway. Traditionally, nitric was thought to signal exclusively via stimulation guanylyl cyclase, inducing increase in intracellular cGMP levels and, turn, allosteric activation cGMPdependent (protein G [PKG]). However, more recent work has revealed some NO·’s can also be transduced by S-nitros(yl)ation nitrosation. Moreover, addition PKG, cGMP-dependent mediated other proteins whose activities are allosterically modified (e.g., phosphodiesterases channels), cross-activation cAMP-dependent A [PKA]). This chapter will cover specific on pathways smooth muscle cells, cardiomyocytes, endothelial platelets.
springer.com
sci-hub.st 参考文章(111)
E. Fujii, Kaoru Irie, Ken-ichi Ohba, Akira Ogawa, Toshimasa Yoshioka, Mitsunori Yamakawa, Takamura Muraki, Role of nitric oxide, prostaglandins and tyrosine kinase in vascular endothelial growth factor-induced increase in vascular permeability in mouse skin Naunyn-schmiedebergs Archives of Pharmacology. ,vol. 356, pp. 475- 480 ,(1997) , 10.1007/PL00005079
Midori Awazu, Inhibition of platelet-derived growth factor receptor tyrosine kinase by atrial natriuretic peptide Kidney International. ,vol. 52, pp. 356- 362 ,(1997) , 10.1038/KI.1997.341
Susanne Mohr, Jonathan S. Stamler, Bernhard Brüne, Mechanism of covalent modification of glyceraldehyde‐3‐phosphate dehydrogenase at its active site thiol by nitric oxide, peroxynitrite and related nitrosating agents FEBS Letters. ,vol. 348, pp. 223- 227 ,(1994) , 10.1016/0014-5793(94)00596-6
S. L. Archer, J. M. Huang, V. Hampl, D. P. Nelson, P. J. Shultz, E. K. Weir, Nitric oxide and cGMP cause vasorelaxation by activation of a charybdotoxin-sensitive K channel by cGMP-dependent protein kinase Proceedings of the National Academy of Sciences of the United States of America. ,vol. 91, pp. 7583- 7587 ,(1994) , 10.1073/PNAS.91.16.7583
Andrew Delatorre, Rebecca A. Schroeder, Paul C. Kuo, Alteration of NF-κB p50 DNA Binding Kinetics by S-Nitrosylation☆ Biochemical and Biophysical Research Communications. ,vol. 238, pp. 703- 706 ,(1997) , 10.1006/BBRC.1997.7279
Jianrong Li, Timothy R. Billiar, Robert V. Talanian, Young M. Kim, Nitric Oxide Reversibly Inhibits Seven Members of the Caspase Family via S-Nitrosylation Biochemical and Biophysical Research Communications. ,vol. 240, pp. 419- 424 ,(1997) , 10.1006/BBRC.1997.7672
Victoria M. Bolotina, Soheil Najibi, James J. Palacino, Patrick J. Pagano, Richard A. Cohen, Nitric oxide directly activates calcium-dependent potassium channels in vascular smooth muscle Nature. ,vol. 368, pp. 850- 853 ,(1994) , 10.1038/368850A0
Eileen M. Redmond, Paul A. Cahill, Robert Hodges, Shuangmin Zhang, James V. Sitzmann, Regulation of endothelin receptors by nitric oxide in cultured rat vascular smooth muscle cells Journal of Cellular Physiology. ,vol. 166, pp. 469- 479 ,(1996) , 10.1002/(SICI)1097-4652(199603)166:3<469::AID-JCP1>3.0.CO;2-N
E H Lieberman, S O'Neill, M E Mendelsohn, S-nitrosocysteine inhibition of human platelet secretion is correlated with increases in platelet cGMP levels. Circulation Research. ,vol. 68, pp. 1722- 1728 ,(1991) , 10.1161/01.RES.68.6.1722
Henning Schröder, Hans Strobach, Karsten Schrör, Nitric oxide but not prostacyclin is an autocrine endothelial mediator Biochemical Pharmacology. ,vol. 43, pp. 533- 537 ,(1992) , 10.1016/0006-2952(92)90575-4