Structure Prediction of Binding Sites of MHC Class II Molecules based on the Crystal of HLA-DRB1 and Global Optimization

作者: M. G. Ierapetritou , I. P. Androulakis , D. S. Monos , C. A. Floudas

DOI: 10.1007/978-1-4757-3218-4_10

关键词:

摘要: Class II histocompatibility molecules are cell surface that form complexes with self and non-self peptides present them to T-cells activate the immune response. A number of class have been analyzed by crystallography include HLA-DR1 [59], HLA-DR3 [22], I-E k [21].

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