Conformational changes associated with protein-protein interactions.

作者: Chern-Sing Goh , Duncan Milburn , Mark Gerstein

DOI: 10.1016/J.SBI.2004.01.005

关键词:

摘要: Abstract Motions related to protein–protein binding events can be surveyed from the perspective of Database Macromolecular Movements. There are a number alternative conceptual models that describe these events, particularly induced fit and pre-existing equilibrium. is evidence for both alternatives recent studies conformational change. However, there increasing support equilibrium model, whereby proteins found simultaneously exist in populations diverse conformations.

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