Micronucleus frequency and lipid peroxidation in Allium sativum root tip cells treated with gibberellic acid and cadmium
作者： Ayla Çelik , Serpil Ünyayar , Fazilet Özlem Çekiç , Ayşin Güzel
DOI: 10.1007/S10565-007-9025-Y
关键词:
摘要: Gibberellic acid (GA3) is a very potent hormone whose natural occurrence in plants controls their development. Cadmium particularly dangerous pollutant due to its high toxicity and great solubility water. In this study, the effect of GA3 on Allium sativum root tip cells was investigated presence cadmium. A. were exposed CdNO3 (50, 100, 200 μM), (10-3 M), both GA3. Cytogenetic analyses performed as micronucleus (MN) assay mitotic index (MI). Lipid peroxidation analysis also for determination membrane damage. MN exhibited dose-dependent increase Cd treatments sativum. significantly reduced frequency. observed + 50 μm at low MI slightly decreased treatments. more concentrations than combined The cadmium induce MN, lipid lead genotoxicity Current work reveals that can be partially restored with application.
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