Phase I study of cetuximab in combination with 5-fluorouracil, mitomycin C and radiotherapy in patients with locally advanced anal cancer.

作者: Otilia Leon , Marianne G. Guren , Calin Radu , Adalsteinn Gunnlaugsson , Anders Johnsson

DOI: 10.1016/J.EJCA.2015.08.029

关键词:

摘要: 5-fluorouracil (5FU) and mitomycin C (MMC)-based chemoradiotherapy (CRT) is standard treatment for anal squamous cell carcinoma. In this phase I study cetuximab was added the primary aim to determine maximum tolerated dose (MTD) of 5FU MMC in combination.

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