Arthropathy of genetic hemochromatosis: a major and distinctive manifestation of the disease.

摘要: Genetic hemochromatosis is not a rare disease and represents frequently underestimated cause of arthropathy. Joint involvement one the most frequent manifestations presents typical clinical radiological features that strongly suggest diagnosis. complaints are often first manifestation GH. Their identification may be crucial to establish diagnosis in pre-cirrhotic phase institute appropriate therapy prevent organ damage associated mortality. Recent genetic defect responsible for leading new insights into pathogenesis GH