Label-Free Detection of Hemoglobin Using MWNT-Embedded Screen-Printed Electrode
作者： Deepika Bhatnagar , Satish K. Tuteja , Richa Rastogi , Lalit M. Bharadwaj
DOI: 10.1007/S12668-013-0095-4
关键词:
摘要: The synthesis of a network cross-linked multiwalled carbon nanotubes (MWNTs) on cysteamine-functionalized screen-printed gold electrode (MWNT/Au-SPE) and its use as sensor for hemoglobin (Hb) determination is reported. It proved to be ready-to-use platform routine clinical analysis in the blood after separation red cells. study shows direct electron transfer between Hb-FeIII Hb-FeII applying potential difference which beneficial detecting presence Hb solution. characterization MWNT-embedded was accomplished through Fourier transform infrared spectroscopy, field emission scanning microscopy, energy dispersive X-ray electrochemical impedance spectroscopy (EIS), Raman optical profiling, cyclic voltammetry. EIS studies show reduction value surface charge resistance (Rct) from MWNT/Au-SPE (−2.72 kΩ) bare Au-SPE (−24.38 kΩ), respectively. showed better characteristics, kinetic revealed heterogeneous rate constant (ks) 1.26 s−1. electrochemically active area also increased 100 times (2.41 × 10−6 cm2) (2.052 10−4 cm2). sensitivity found 20.50 μA g−1 dl linear range 9–15 g dl−1 lyophilized Hb. extremely sensitive samples with 38.75 same range.
springer.com
sci-hub.se 参考文章(39)
Wenjie Liang, Marc Bockrath, Dolores Bozovic, Jason H. Hafner, M. Tinkham, Hongkun Park, Fabry - Perot interference in a nanotube electron waveguide Nature. ,vol. 411, pp. 665- 669 ,(2001) , 10.1038/35079517
Jiannong. Ye, Richard P. Baldwin, Catalytic reduction of myoglobin and hemoglobin at chemically modified electrodes containing methylene blue. Analytical Chemistry. ,vol. 60, pp. 2263- 2268 ,(1988) , 10.1021/AC00171A021
Junmo Kang, Hitomi Yamaguchi, Internal finishing of capillary tubes by magnetic abrasive finishing using a multiple pole-tip system Precision Engineering-journal of The International Societies for Precision Engineering and Nanotechnology. ,vol. 36, pp. 510- 516 ,(2012) , 10.1016/J.PRECISIONENG.2012.01.006
Chenghong Lei, Ulla Wollenberger, Nikitas Bistolas, Anthony Guiseppi-Elie, Frieder Scheller, Electron transfer of hemoglobin at electrodes modified with colloidal clay nanoparticles. Analytical and Bioanalytical Chemistry. ,vol. 372, pp. 235- 239 ,(2002) , 10.1007/S00216-001-1200-Z
Yuezhong Xian, Yang Xian, Lihui Zhou, Fanghua Wu, Yun Ling, Litong Jin, Encapsulation hemoglobin in ordered mesoporous silicas: Influence factors for immobilization and bioelectrochemistry Electrochemistry Communications. ,vol. 9, pp. 142- 148 ,(2007) , 10.1016/J.ELECOM.2006.08.049
Richa Rastogi, Navneet Dhindsa, C. Raman Suri, B.D. Pant, S.K. Tripathi, Inderpreet Kaur, Lalit M. Bharadwaj, Interfacing of DNA with carbon nanotubes for nanodevice applications Materials Chemistry and Physics. ,vol. 135, pp. 268- 276 ,(2012) , 10.1016/J.MATCHEMPHYS.2012.05.020
Wei Sun, Peng Qin, Ruijun Zhao, Kui Jiao, Direct electrochemistry and electrocatalysis of hemoglobin on gold nanoparticle decorated carbon ionic liquid electrode. Talanta. ,vol. 80, pp. 2177- 2181 ,(2010) , 10.1016/J.TALANTA.2009.11.026
P. Prabhu, R. Suresh Babu, S. Sriman Narayanan, Electrocatalytic oxidation of l-tryptophan using copper hexacyanoferrate film modified gold nanoparticle graphite-wax electrode Colloids and Surfaces B: Biointerfaces. ,vol. 87, pp. 103- 108 ,(2011) , 10.1016/J.COLSURFB.2011.05.008
Frieder W. Scheller, Nikitas Bistolas, Songqin Liu, Michael Jänchen, Martin Katterle, Ulla Wollenberger, Thirty years of haemoglobin electrochemistry Advances in Colloid and Interface Science. ,vol. 116, pp. 111- 120 ,(2005) , 10.1016/J.CIS.2005.05.006
E. Laviron, General expression of the linear potential sweep voltammogram in the case of diffusionless electrochemical systems Journal of Electroanalytical Chemistry. ,vol. 101, pp. 19- 28 ,(1979) , 10.1016/S0022-0728(79)80075-3