Key aspects of PCSK9 inhibition beyond LDL lowering

作者: Stéphane Ramin-Mangata , Valentin Blanchard , Gilles Lambert

DOI: 10.1097/MOL.0000000000000551

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摘要: … This hypothesis is underpinned by Mendelian randomization studies showing that genetic variants in HMGCR and PCSK9 that confer lifelong reductions in LDL-C levels and are thus …

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