作者: Mojdeh S. Heavner , Min Zhang , Chelsea E. Bast , Lindsey Parker , Rachel F. Eyler
DOI: 10.1002/PHAR.2025
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摘要: Pregnant women are at high risk for venous thromboembolism, including pulmonary embolism (PE), given expected changes in coagulation, fibrinolysis, and blood flow. In fact, PE is the leading cause of maternal death United States. Nonpregnant patients who develop with hypotension or show signs deterioration after anticoagulation receive thrombolytics as a standard care. women, however, have been excluded from clinical trials thrombolytics, all data available this population published case reports series. We reviewed systemic catheter directed, used pregnant massive PE. This article summarizes risks thromboembolism pregnancy, compares contrasts thrombolytic agents setting, provides recommendation management special population. Overall, suggest that use these associated beneficial outcomes relatively low complications. The quality evidence low, judgment required to assess individual versus benefits thrombolysis.