Effect of Drugs upon Axoplasmic Transport

作者: William O. McClure

DOI: 10.1016/S1054-3589(08)60524-4

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摘要: Publisher Summary This chapter discusses the effect of drugs upon axoplasmic transport. Axoplasmic transport is a neural activity ever-increasing interest to biochemist and physiologist. To understand functions transported molecules manner in which they interact with axon synapse, employ agents that disrupt shall have be employed. Several classes such are now available: inhibitors karyokinesis, as colchicine; antimetabolites, dinitrophenol; important but poorly studied compounds, neuropathogens. New types methoxylated phenalkylamines, becoming available. Agents about much known suggest proteins synthesized ribosomes using messenger RNA, is, turn, coded from DNA. Transport requires use metabolic energy, probably derived carbohydrates through respiration. The act involves intra-axonal filamentous structures, microtubules microfilaments most strongly implicated.

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