Tumor Microvasculature and Microenvironment: Novel Insights Through Intravital Imaging in Pre‐Clinical Models

作者: DAI FUKUMURA , DAN G. DUDA , LANCE L. MUNN , RAKESH K. JAIN

DOI: 10.1111/J.1549-8719.2010.00029.X

关键词:

摘要: … IVM imaging in combination with sophisticated genetic models and animal preparations (eg, … in response to the exposed microenvironment. These local interactions vary with tumor type …

参考文章(166)
Rakesh K. Jain, Lance L. Munn, Dai Fukumura, Dissecting tumour pathophysiology using intravital microscopy Nature Reviews Cancer. ,vol. 2, pp. 266- 276 ,(2002) , 10.1038/NRC778
Thea D Tlsty, Stromal cells can contribute oncogenic signals Seminars in Cancer Biology. ,vol. 11, pp. 97- 104 ,(2001) , 10.1006/SCBI.2000.0361
S. K. Hobbs, W. L. Monsky, F. Yuan, W. G. Roberts, L. Griffith, V. P. Torchilin, R. K. Jain, Regulation of transport pathways in tumor vessels: Role of tumor type and microenvironment Proceedings of the National Academy of Sciences of the United States of America. ,vol. 95, pp. 4607- 4612 ,(1998) , 10.1073/PNAS.95.8.4607
Chuan-Yuan Li, Siqing Shan, Qian Huang, Rod D. Braun, Jennifer Lanzen, Kang Hu, Pengnian Lin, Mark W. Dewhirst, Initial Stages of Tumor Cell-Induced Angiogenesis: Evaluation Via Skin Window Chambers in Rodent Models Journal of the National Cancer Institute. ,vol. 92, pp. 143- 147 ,(2000) , 10.1093/JNCI/92.2.143
Hera C. Lichtenbeld, Napoleone Ferarra, Rakesh K. Jain, Lance L. Munn, Effect of local anti-VEGF antibody treatment on tumor microvessel permeability. Microvascular Research. ,vol. 57, pp. 357- 362 ,(1999) , 10.1006/MVRE.1998.2140
J. Y. Perentes, D. G. Duda, R. K. Jain, Visualizing anti-tumor immune responses in vivo. Disease Models & Mechanisms. ,vol. 2, pp. 107- 110 ,(2009) , 10.1242/DMM.001842
Benjamin J Vakoc, Ryan M Lanning, James A Tyrrell, Timothy P Padera, Lisa A Bartlett, Triantafyllos Stylianopoulos, Lance L Munn, Guillermo J Tearney, Dai Fukumura, Rakesh K Jain, Brett E Bouma, Three-dimensional microscopy of the tumor microenvironment in vivo using optical frequency domain imaging. Nature Medicine. ,vol. 15, pp. 1219- 1223 ,(2009) , 10.1038/NM.1971
Rakesh K Jain, Dan G Duda, Jeffrey W Clark, Jay S Loeffler, Lessons from phase III clinical trials on anti-VEGF therapy for cancer Nature Reviews Clinical Oncology. ,vol. 3, pp. 24- 40 ,(2006) , 10.1038/NCPONC0403
G.Y. Fan, H. Fujisaki, A. Miyawaki, R.-K. Tsay, Roger Y. Tsien, Mark H. Ellisman, Video-rate scanning two-photon excitation fluorescence microscopy and ratio imaging with cameleons Biophysical Journal. ,vol. 76, pp. 2412- 2420 ,(1999) , 10.1016/S0006-3495(99)77396-0
Rakesh K. Jain, Gerald C. Koenig, Marc Dellian, Dai Fukumura, Lance L. Munn, Robert J. Melder, Leukocyte-endothelial adhesion and angiogenesis in tumors Cancer and Metastasis Reviews. ,vol. 15, pp. 195- 204 ,(1996) , 10.1007/BF00437472