An hourglass design with electrokinetic sampling and electrothermal actuation for micro biosensors
作者： Stephane Leahy , Yongjun Lai
DOI: 10.1016/J.SNB.2015.09.045
关键词:
摘要: Abstract An hourglass design that enables electrokinetic sampling and electrothermal actuation for detecting waterborne pathogens with micro biosensors is presented. The component creates a large potential drop suitable dielectrophoresis serves as V-shaped microelectrothermal actuator structural measurements. Escherichia coli bacteria from stagnant 5 μl sample were collected within 15 min signal of 5 V peak-to-peak (Vpp) at 1 kHz. detected by measuring resonant frequency shifts the first eight modes microstructure, maximum sensitivity 20.4 ± 5.3 fg/Hz was achieved seventh mode. unique solution combines excitation biosensors.
sci-hub.se 参考文章(27)
René Lalauze, Chemical sensors and biosensors ISTE , Wiley. ,(2012)
Antonio RAMOS, Electrokinetics and electrohydrodynamics in microsystems Springer Vienna. ,(2011) , 10.1007/978-3-7091-0900-7
William Tyrrell Thomson, Theory of vibration with applications ,(1965)
Søren Dohn, Rasmus Sandberg, Winnie Svendsen, Anja Boisen, None, Enhanced functionality of cantilever based mass sensors using higher modes Applied Physics Letters. ,vol. 86, pp. 233501- ,(2005) , 10.1063/1.1948521
Mar Alvarez, Laura M. Lechuga, Microcantilever-based platforms as biosensing tools Analyst. ,vol. 135, pp. 827- 836 ,(2010) , 10.1039/B908503N
B. Ilic, D. Czaplewski, M. Zalalutdinov, H. G. Craighead, P. Neuzil, C. Campagnolo, C. Batt, Single cell detection with micromechanical oscillators Journal of Vacuum Science & Technology B. ,vol. 19, pp. 2825- 2828 ,(2001) , 10.1116/1.1421572
Gossett A. Campbell, Raj Mutharasan, Piezoelectric-excited millimeter-sized cantilever (PEMC) sensors detect Bacillus anthracis at 300 spores/mL. Biosensors and Bioelectronics. ,vol. 21, pp. 1684- 1692 ,(2006) , 10.1016/J.BIOS.2005.08.001
John Elie Sader, Frequency response of cantilever beams immersed in viscous fluids with applications to the atomic force microscope Journal of Applied Physics. ,vol. 84, pp. 64- 76 ,(1998) , 10.1063/1.368002
Matthew R. Tomkins, Jacky Chow, Yongjun Lai, Aristides Docoslis, A coupled cantilever-microelectrode biosensor for enhanced pathogen detection Sensors and Actuators B-chemical. ,vol. 176, pp. 248- 252 ,(2013) , 10.1016/J.SNB.2012.09.020
Gossett A. Campbell, Raj Mutharasan, Detection and quantification of proteins using self-excited PZT-glass millimeter-sized cantilever Biosensors and Bioelectronics. ,vol. 21, pp. 597- 607 ,(2005) , 10.1016/J.BIOS.2004.12.016