In vivo voltammetry: monitoring of dopamine metabolites in CSF following release by electrical stimulation.
作者： R. Mark Wightman , Elaine Strope , Paul Plotsky , Ralph N. Adams
DOI: 10.1016/0006-8993(78)90109-9
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摘要: An in vivo electrochemical system which continuously records the concentration of metabolites biogenic amines small animal CSF is described. A electrode, immersed lateral ventricle through a guide cannula, measures amine by voltammetric oxidation. The detailed results HVA release following electrical stimulation nigrostriatal pathway rats are presented and compared with previous perfusion data. All verified independent liquid chromatographic (chemical) analysis.
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