Fusion of Cell Fragments as a Method in Cell Genetics

摘要: Prior to the early sixties mammalian genetics had been concerned almost exclusively with mechanisms by which genetic information was transmitted through germ cells. Although this is still a central area recent technical developments now make it possible analyze organization and function of genes in somatic Somatic cell new subfield aims define involved differentiation, neoplasia, inborn errors metabolism, cell-virus interactions other hereditary phenomena The methodology field includes generation selection mutant lines, phenotypic analysis cultured cells, hybridization gene transfer methods mention but few currently used.