Micro- and Nanospheres for Tissue Engineering

作者: Huanan Wang , Sander C.G. Leeuwenburgh , Yubao Li , John A. Jansen

DOI: 10.1002/9781118574775.CH9

关键词:

摘要: The emergence of regenerative medicine has resulted in a novel interdisciplinary field that focuses on repair, replacement, and regeneration diseased or damaged tissues organs. As one the most important strategies medicine, tissue engineering (which typically combines biodegradable scaffolds, (stem) cells, bioactive signals such as growth factors) created new possibilities to produce implantable ex vivo. This chapter recent advances research micro- nanospheres aiming at improvement functionality clinical efficacy traditional scaffolds for soft hard engineering. Depending their origin, polymeric can be classified either natural synthetic polymers, both which have specific pros cons.

参考文章(109)
Xiaoqin Wang, Esther Wenk, Xiaohui Zhang, Lorenz Meinel, Gordana Vunjak-Novakovic, David L. Kaplan, Growth factor gradients via microsphere delivery in biopolymer scaffolds for osteochondral tissue engineering Journal of Controlled Release. ,vol. 134, pp. 81- 90 ,(2009) , 10.1016/J.JCONREL.2008.10.021
A.K. Lynn, I.V. Yannas, W. Bonfield, Antigenicity and immunogenicity of collagen. Journal of Biomedical Materials Research Part B. ,vol. 71, pp. 343- 354 ,(2004) , 10.1002/JBM.B.30096
Yukiko T. Matsunaga, Yuya Morimoto, Shoji Takeuchi, Molding cell beads for rapid construction of macroscopic 3D tissue architecture. Advanced Materials. ,vol. 23, ,(2011) , 10.1002/ADMA.201004375
Tomonori MATSUNO, Yoshiya HASHIMOTO, Seita ADACHI, Kazuhiko OMATA, Yamauchi YOSHITAKA, Yasuyuki OZEKI, Yoshikazu UMEZU, Yasuhiko TABATA, Masaaki NAKAMURA, Tazuko SATOH, Preparation of injectable 3D-formed beta-tricalcium phosphate bead/alginate composite for bone tissue engineering. Dental Materials Journal. ,vol. 27, pp. 827- 834 ,(2008) , 10.4012/DMJ.27.827
Raghavendra C Mundargi, V Ramesh Babu, Vidhya Rangaswamy, Pradip Patel, Tejraj M Aminabhavi, None, Nano/micro technologies for delivering macromolecular therapeutics using poly(D,L-lactide-co-glycolide) and its derivatives. Journal of Controlled Release. ,vol. 125, pp. 193- 209 ,(2008) , 10.1016/J.JCONREL.2007.09.013
Francesca Ungaro, Marco Biondi, Ivana d'Angelo, Laura Indolfi, Fabiana Quaglia, Paolo Antonio Netti, Maria Immacolata La Rotonda, Microsphere-integrated collagen scaffolds for tissue engineering: Effect of microsphere formulation and scaffold properties on protein release kinetics Journal of Controlled Release. ,vol. 113, pp. 128- 136 ,(2006) , 10.1016/J.JCONREL.2006.04.011
Sophie R. Van Tomme, Ad Mens, Cornelus F. van Nostrum, Wim E. Hennink, Macroscopic hydrogels by self-assembly of oligolactate-grafted dextran microspheres. Biomacromolecules. ,vol. 9, pp. 158- 165 ,(2008) , 10.1021/BM700931Q
Qun Wang, Jinxi Wang, Qinghua Lu, Michael Scott Detamore, Cory Berkland, None, Injectable PLGA based colloidal gels for zero-order dexamethasone release in cranial defects Biomaterials. ,vol. 31, pp. 4980- 4986 ,(2010) , 10.1016/J.BIOMATERIALS.2010.02.052
Michael D Weir, Hockin HK Xu, None, Human bone marrow stem cell-encapsulating calcium phosphate scaffolds for bone repair Acta Biomaterialia. ,vol. 6, pp. 4118- 4126 ,(2010) , 10.1016/J.ACTBIO.2010.04.029
Aline Fischer, Andrea Franco, Thomas Oberholzer, Giant Vesicles as Microreactors for Enzymatic mRNA Synthesis ChemBioChem. ,vol. 3, pp. 409- 417 ,(2002) , 10.1002/1439-7633(20020503)3:5<409::AID-CBIC409>3.0.CO;2-P