Current developments in pediatric liver transplantation

摘要: In 1953, the pioneer of human orthotopic liver transplantation (LT), Thomas E Starzl, was first to attempt an transplant into a 3 years old patient suffering from biliary atresia. Thus, LT in humans attempted disease, which, up until today, remains main indication for pediatric (pLT). During last sixty years, refinements diagnostics and surgical technique, introduction new immunosuppressive medications improvements perioperative care have established as routine procedure childhood acute chronic failure well inherited diseases. contrast adult recipients, pLT differs greatly indications LT, allocation practice, immunosuppression post-operative life-long aftercare. Many aspects are focus ongoing preclinical clinical research. The present review gives overview current developments outcome pLT, with on alternatives full-size deceased-donor organ transplantation.