Benefit of Intracystic Bleomycin for Symptomatic Recurrent Rathke Cleft Cyst.

摘要: Background Management of recurrent Rathke cleft cysts (RCC) is problematic. The mainstay treatment has been reoperation with cyst drainage. Radical resection, although effective, results in a high incidence diabetes insipidus. Several case reports suggest potential benefit to radiation therapy or the use intracystic bleomycin. application bleomycin known be beneficial cystic craniopharyngioma; however, its usefulness RCC yet proven. Objective To present our 6-yr experience using for RCC. Methods We performed retrospective chart review patients who underwent surgical resection between January 2010 and May 2016 by single surgeon. Specific attention was paid Results Of 59 operated on during this interval, 6 symptomatic were identified received at time reoperation. date, no recurrence documented receiving (mean = 38.8 mo, range 21.2-79.8 mo). Conclusion appears safe potentially effective option Additional studies longer follow-up are needed further define role