Morphomic analysis for preoperative donor site risk assessment in patients undergoing abdominal perforator flap breast reconstruction: a proof of concept study.

摘要: Background  Morphomics are three-dimensional measurements of aspects the human anatomy generated by computed tomographic (CT) imaging. The purpose this study was to generate preliminary data on efficacy morphomics, as a potential risk stratification tool, in predicting abdominal donor site wound-healing complications patients undergoing perforator flap breast reconstruction. Patients and Methods  In total, 58 consecutive deep inferior epigastric (DIEP) reconstruction were evaluated. Using preoperative CT scan data, we quantified patients' body area, visceral subcutaneous fat, fascia depth between T12 L4. Associations morphomic measures complication rates examined using t -tests logistic regression. Results  Of patients, 11 (19%) developed wound dehiscence 47 (81%) healed their incision without complications. with had significantly higher mass index (BMI) (34.32 vs. 29.26 kg/m 2 , p  = 0.014) than dehiscence. Multiple morphometric including fat area (  = 0.003) significant predictors BMI (odds ratio [OR], 1.16; 95% confidence interval [CI], 1.03–1.32;  = 0.017) (OR, 1.24; CI, 1.08–1.42;  = 0.002) independently for entire sample. Only retained its predictive ability BMI > 30 . Conclusions  Morphomic correlate likelihood developing postoperative after DIEP As proof concept study, demonstrates that objective obtained from scans may help preoperatively assessing healing