Population Structure of Pathogenic Bacteria

摘要: Population structure is defined by the organization of genetic variation and driven combined effects evolutionary processes that include recombination, mutation, drift, demographic history, natural selection. In this chapter, authors discuss how population boundaries within species pathogenic bacteria are delineated, contribution to formation distinct, or sometimes fuzzy, populations. The highlight some studies have been aided advancements in whole-genome sequencing broadened our understanding bacterial structure. also describe genomic analysis tools available investigate structure, attempt show study has important applications for effective infection control, public health interventions, antimicrobial vaccine development.