Expression systems using mammalian beta-actin promoter
作者： Kiyoshi Chugai Seiyaku K. K. Habu , Hiroyuki Chugai Seiyaku K. K. Tsunoda
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摘要: Promoter activities were examined by comparing combinations of promoters and enhancers derived from various genes. A hybrid promoter comprising a combination CMV enhancer mammalian β-actin promoter, or the post-transcriptional regulatory region genomic sequence Woodchuck Hepatitis Virus (WPRE) was found to be stronger than existing promoters. Furthermore, could enhanced coexpressing oncogene product Ras, which is transactivator.
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