Community-acquired respiratory infections are common in patients with non-Hodgkin lymphoma and multiple myeloma

摘要: Available data suggest that respiratory infections are associated with increased morbidity and mortality in patients hospitalized due to acute leukemia allogeneic stem cell transplantation (allo-SCT). However, the precise incidence, risk factors, severity of infection, mainly community-acquired, lymphoma multiple myeloma (MM) not fully determined. The current study aimed investigate factors for their clinical significance B non-Hodgkin (NHL) first year diagnosis. Data consecutive diagnosed NHL or MM treated at Rambam Hematology Inpatient Outpatient Units between 01/2011 03/2012 were evaluated. Information regarding anticancer treatment, incidence course infections, infection-related outcomes was analyzed. One hundred sixty episodes recorded 103 (49%) 211 (73-MM, 138-NHL) patients; 126 (79%) 47 (29%) them required hospitalization. In univariate analysis, age < 60 years, diagnosis, autologous SCT infection (P = 0.058, 0.038, 0.001, respectively). Ninety (56% all episodes) examined viral pathogens. Viral documented 25/90 (28%) episodes, 21 (84%) requiring hospitalization 5 (24%) cases. Anti-flu vaccination performed 119 (56%) patients. Two six influenza vaccinated. Respiratory including ones, common MM. Most community-acquired have a favorable outcome. Rapid identification pathogens allows avoiding antibiotic overuse this patient population.