Kinetic Barriers and the Self‐organization of Life

作者: Robert Pascal

DOI: 10.1002/IJCH.201400193

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摘要: This review is devoted to an analysis of the consequences Eschenmoser view that origin life requires a chemical environment held far from equilibrium by kinetic barriers. The corresponding conditions, in which replicating entities comply with specific form stability, are considered terms temperature and potential sources energy capable feeding system. need for irreversibility reproduction cycles emphasized as condition effective selection. High turnover rates cyclic processes would facilitate development reproducing themselves. A preference given here involving selective catalytic pathways, rather than increase likely preferentially noncatalytic degradation pathways. Accordingly, emphasis placed on direct or induced intramolecular Lastly, barriers help reveal nature carriers.

参考文章(65)
Anthony J. Kirby, Effective Molarities for Intramolecular Reactions Advances in Physical Organic Chemistry. ,vol. 17, pp. 183- 278 ,(1980) , 10.1016/S0065-3160(08)60129-X
William P. Jencks, Binding Energy, Specificity, and Enzymic Catalysis: The Circe Effect Advances in Enzymology - and Related Areas of Molecular Biology. ,vol. 43, pp. 219- 410 ,(1975) , 10.1002/9780470122884.CH4
Jeffrey L Bada, Antonio Lazcano, Some Like It Hot, But Not the First Biomolecules Science. ,vol. 296, pp. 1982- 1983 ,(2002) , 10.1126/SCIENCE.1069487
R. B. Stockbridge, C. A. Lewis, Y. Yuan, R. Wolfenden, Impact of temperature on the time required for the establishment of primordial biochemistry, and for the evolution of enzymes. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 107, pp. 22102- 22105 ,(2010) , 10.1073/PNAS.1013647107
W. John Albery, Jeremy R. Knowles, Evolution of enzyme function and the development of catalytic efficiency Biochemistry. ,vol. 15, pp. 5631- 5640 ,(1976) , 10.1021/BI00670A032
Kian L. Tan, Catalysis: Temporary intramolecularity Nature Chemistry. ,vol. 4, pp. 253- 254 ,(2012) , 10.1038/NCHEM.1308
Ziwei Liu, Damien Beaufils, Jean-Christophe Rossi, Robert Pascal, Evolutionary Importance of the Intramolecular Pathways of Hydrolysis of Phosphate Ester Mixed Anhydrides with Amino Acids and Peptides Scientific Reports. ,vol. 4, pp. 7440- 7440 ,(2015) , 10.1038/SREP07440
Luke J. Leman, Leslie E. Orgel, M. Reza Ghadiri, Amino Acid Dependent Formation of Phosphate Anhydrides in Water Mediated by Carbonyl Sulfide Journal of the American Chemical Society. ,vol. 128, pp. 20- 21 ,(2006) , 10.1021/JA056036E