Copper(II) complexes supported by click generated mixed NN, NO, and NS 1,2,3-triazole based ligands and their catalytic activity in azide–alkyne cycloaddition

摘要: The preparation and characterization of four new copper(II) complexes supported by click generated mixed NN, NO, NS 1,2,3-triazoles are reported. display a 1 : 2 copper/ligand ratio give monomeric units in the solid state. Crystal structures demonstrate that depending on flexibility ligand NX (X = O, N, S) pendant arm, coordination environment around metal center can feature square planar or octahedral geometries. All catalytically active at room temperature copper-catalyzed alkyne–azide cycloaddition (CuAAC) reaction using sodium ascorbate as reducing agent water–ethanol solvent mixture. Complex 8 displayed best catalytic performance series allowing for easy high yielding variety mono-, bis- tris-1,2,3-triazoles under low catalyst loadings.