Comparison of Optical Coherence Tomography and Ultrasound Biomicroscopy for Detection of Narrow Anterior Chamber Angles

摘要: Objective To assess the accuracy of classification narrow anterior chamber (AC) angles using quantitative imaging by optical coherence tomography (OCT) and ultrasound biomicroscopy (UBM). Design Observational comparative study. Methods A high-speed (4000 axial scans/s) segment OCT prototype was developed a 1.3-μm light source. Seventeen normal subjects (17 eyes) 7 (14 with angle glaucoma were enrolled. All underwent gonioscopy, OCT, UBM. Quantitative AC parameters (angle opening distance, recess area, trabecular-iris space area [a new parameter we have defined]) measured from UBM images proprietary processing software. Main Outcome Measures Specificity sensitivity in identifying image-derived parameters. Results Eight 31 eyes classified as having (Shaffer grade ≤1 all quadrants). The both had similar mean values, reproducibility, sensitivity-specificity profiles. Both showed excellent performance angles. Areas under receiver operating characteristic curves for these range 0.96 to 0.98. Conclusions Optical measurement detection In addition, it easier use did not require contact eye. is promising method screening individuals at risk glaucoma.