The Challenge of Neurocognitive Dysfunction in Severe Heart Failure

摘要: Often ignored, neurocognitive dysfunction in chronic heart failure represents a daunting morbidity progressing to loss of self-reliance. Although the precise mechanisms arbitrating development this disorder remain elusive, microembolization and cerebral hypoperfusion are implicated. Other causes cognitive decline may include prior cardiac surgery, hypertension, sleep disordered breathing, hyperhomocysteinemia, dementia aging, more traditional such as Alzheimer's disease. The discovery defects must prompt well-constructed diagnostic evaluation search for underlying since process be at least partially reversible many cases.