Solitary and multiple erythema migrans in children: comparison of demographic, clinical and laboratory findings.

摘要: Data on European children with erythema migrans (EM) are limited. 553 patients, 333 solitary and 220 multiple EM, diagnosed between 1996 2000, were included in the prospective study. Demographic, clinical laboratory data including borrelial serum immunofluorescence assay antibody titers Borrelia burgdorferi sensu lato blood culture results were obtained; findings EM were compared. Comparison revealed that were younger (4.5 vs 6.5 years; p = 0.0000), less often reported a tick bite at the site of later skin lesion (25% 46%; = 0.0000), had a longer incubation period (22 13 days; = 0.0028), more frequently presented ringlike (99% vs 86%; associated local (15% vs 41%; 0.0000) but not systemic symptoms (28% 26%, = 0.6913), abnormal physical examination (35% 26%; 0.0264), higher frequency of laboratory abnormalities including presence borrelial serum antibodies as well B. burgdorferi isolated from (12% vs 6%; 0.0267); younger age male sex identified as risk factors for isolation Borrelia. 40/44 isolates were Borrelia afzelii. Analysis large group with solitary several demographic, clinical and differences two groups.