Chemo- and diastereoselective epoxidation of allylic alcohols with a titania–silica aerogel

摘要: Abstract An amorphous mesoporous titania–silica aerogel (20 wt.% TiO 2 –80 SiO ) and tert -butylhydroperoxide have been used for the epoxidation of various allylic alcohols. Cyclic alcohols alkenols possessing an internal double bond were more reactive than with a terminal CC bond. Epoxide selectivities could be improved by catalyst pre-drying hydrophobisation in toluene, as well addition (basic) zeolite 4A NaHCO 3 to reaction mixture. Diastereoselective cyclic yielded preferentially cis -epoxides. The performance α-β-unsaturated carbonyl compounds was compared those titania-on-silica TS-1. Interestingly, TS-1 inactive compounds.