Breast conservation therapy in the United States following the 1990 National Institutes of Health Consensus Development Conference on the treatment of patients with early stage invasive breast carcinoma.

摘要: BACKGROUND A National Institutes of Health (NIH) Consensus Development Conference on the treatment patients with early stage invasive breast carcinoma, held in June 1990, recommended conservation therapy for majority women Stage I or II carcinoma. The authors evaluated national use before and after conference to determine whether had an impact utilization. METHODS Women carcinoma (n = 109,880), diagnosed during years 1983–1995, were identified via 9 population-based cancer registries Surveillance, Epidemiology, End Results (SEER) program Cancer Institute. likelihood surgery versus mastectomy and, among who underwent surgery, postoperative radiation none, assessed 3 time periods (January 1983 April 1985, May 1985 July 1990 December 1995). Associations between radiotherapy according patient stage, age, race, region compared NIH Conference. RESULTS From (the year that U.S. randomized controlled trial demonstrating equivalent efficacy was published) through 1989, approximately 35% 19% surgery; these percentages remained constant throughout this period. Beginning Conference, increased each subsequent year; by 1995, 60% 39% received such treatment. However, regional variation observed (Stage I, range 41.4–71.4% 1995) no registry reported disease (range, 23.8–48.0%). similar conference. CONCLUSIONS Although performed more frequently following suggests continued presence barriers widespread adoption recommendations formulated at conference. 1999;86:628–37. © 1999 American Society.