Inhibition of bacterial adhesion on medical devices.

摘要: Microbial infections resulting from bacterial adhesion to biomaterial surfaces have been observed on almost all medical devices. Biofilm pose a number of clinical challenges due their resistance immune defence mechanisms and antimicrobials, and, regardless the sophistication implant, devices are susceptible microbial colonisation infection. Research efforts currently directed towards eliminating or reducing infection Strategies prevent biofilm formation include physiochemical modification surface create anti-adhesive surfaces, incorporation antimicrobial agents into device polymers, mechanical design alternatives, release antibiotics. Nevertheless, success these alternatives has modest, mainly various environments which placed diversity ways in organisms can colonise surfaces. Biosurfactants reported as promising strategy they effectively inhibit retard formation, thus potentially useful new generation coatings for