Family intervention (brief) for schizophrenia

作者: Uzuazomaro Okpokoro , Clive E Adams , Stephanie Sampson

DOI: 10.1002/14651858.CD009802.PUB2

关键词:

摘要: Background Supportive, positive family environments have been shown to improve outcomes for patients with schizophrenia in contrast that express high levels of criticism, hostility, or over-involvement, which poorer and more frequent relapses. Forms psychosocial intervention, designed promote reduce these expressed emotions within families, are now widely used. Objectives To assess the effects brief interventions people schizophrenia-like conditions. Search methods We searched Cochrane Schizophrenia Group Trials Register (July 2012), is based on regular searches CINAHL, EMBASE, MEDLINE PsycINFO. We inspected references all identified studies further trials. contacted authors trials additional information. Selection criteria All relevant randomised compared family-oriented standard care, focusing families schizoaffective disorder were selected. Data collection analysis We reliably selected studies, quality assessed them extracted data. For binary outcomes, we calculated estimates risk ratio (RR) their 95% confidence intervals (CI). continuous estimated a mean difference (MD) between groups CIs. used GRADE evidence main interest created 'Summary findings' table. bias included studies. Main results Four randomising 163 could be review. It not clear if intervention reduces utilisation health services by patients, as most results equivocal at long term only one study reported data primary hospital admission (n = 30, 1 RCT, RR 0.50, CI 0.22 1.11, very low evidence). Data relapse also medium 40, 0.10 2.43, However, outcome understanding member significantly favoured 70, MD 14.90, 7.20 22.60, No other including days hospital; adverse events; medication compliance; life satisfaction care; any economic outcomes. Authors' conclusions The findings this review outstanding due size providing data; analysed minimal, no meta-analysis possible. All table rated evidence. importance should dismissed outright, present state demand resources available. The designs such modified effective larger may then enough power inform clinical practice.

参考文章(60)
D. G Altman, J M. Bland, Detecting skewness from summary information. BMJ. ,vol. 313, pp. 1200- 1200 ,(1996) , 10.1136/BMJ.313.7066.1200
Holger J Schünemann, Gunn E Vist, Julian PT Higgins, Nancy Santesso, Jonathan J Deeks, Paul Glasziou, Elie A Akl, Gordon H Guyatt, Cochrane GRADEing Methods Group, Interpreting results and drawing conclusions Cochrane Handbook for Systematic Reviews of Interventions. pp. 359- 387 ,(2019) , 10.1002/9780470712184.CH12
FM Pharoah, J Rathbone, JJ Mari, D Streiner, Family intervention for schizophrenia Cochrane Database of Systematic Reviews. ,(2010) , 10.1002/14651858.CD000088
A. Larsen, D.H. Olson, H.I. McCubbin, F-COPES: Family Crisis Oriented Personal Evaluation Scales Family inventories : inventories used in a national survey of families across the family life cycle / [David H. Olson ... [et al.]]. ,(1985)
Stefan Leucht, Werner Kissling, Josef Bäuml, Gabi Pitschel-Walz, Rolf R. Engel, The Effect of Family Interventions on Relapse and Rehospitalization in Schizophrenia: A Meta-Analysis FOCUS. ,(2015)
Toshi A. Furukawa, Corrado Barbui, Andrea Cipriani, Paolo Brambilla, Norio Watanabe, Imputing missing standard deviations in meta-analyses can provide accurate results Journal of Clinical Epidemiology. ,vol. 59, pp. 7- 10 ,(2006) , 10.1016/J.JCLINEPI.2005.06.006
Max Birchwood, Jo Smith, Ray Cochrane, Specific and non-specific effects of educational intervention for families living with schizophrenia. A comparison of three methods. British Journal of Psychiatry. ,vol. 160, pp. 806- 814 ,(1992) , 10.1192/BJP.160.6.806
J M. Bland, S. M Kerry, Statistics notes. Trials randomised in clusters. BMJ. ,vol. 315, pp. 600- 600 ,(1997) , 10.1136/BMJ.315.7108.600