作者: Uzuazomaro Okpokoro , Clive E Adams , Stephanie Sampson
DOI: 10.1002/14651858.CD009802.PUB2
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摘要: Background Supportive, positive family environments have been shown to improve outcomes for patients with schizophrenia in contrast that express high levels of criticism, hostility, or over-involvement, which poorer and more frequent relapses. Forms psychosocial intervention, designed promote reduce these expressed emotions within families, are now widely used. Objectives To assess the effects brief interventions people schizophrenia-like conditions. Search methods We searched Cochrane Schizophrenia Group Trials Register (July 2012), is based on regular searches CINAHL, EMBASE, MEDLINE PsycINFO. We inspected references all identified studies further trials. contacted authors trials additional information. Selection criteria All relevant randomised compared family-oriented standard care, focusing families schizoaffective disorder were selected. Data collection analysis We reliably selected studies, quality assessed them extracted data. For binary outcomes, we calculated estimates risk ratio (RR) their 95% confidence intervals (CI). continuous estimated a mean difference (MD) between groups CIs. used GRADE evidence main interest created 'Summary findings' table. bias included studies. Main results Four randomising 163 could be review. It not clear if intervention reduces utilisation health services by patients, as most results equivocal at long term only one study reported data primary hospital admission (n = 30, 1 RCT, RR 0.50, CI 0.22 1.11, very low evidence). Data relapse also medium 40, 0.10 2.43, However, outcome understanding member significantly favoured 70, MD 14.90, 7.20 22.60, No other including days hospital; adverse events; medication compliance; life satisfaction care; any economic outcomes. Authors' conclusions The findings this review outstanding due size providing data; analysed minimal, no meta-analysis possible. All table rated evidence. importance should dismissed outright, present state demand resources available. The designs such modified effective larger may then enough power inform clinical practice.