Erectile dysfunction: monitoring response to treatment in clinical practice--recommendations of an international study panel

摘要: ABSTRACT Introduction Clinical practice guidelines for management of erectile dysfunction (ED) provide limited direction in defining appropriate treatment goals with phosphodiesterase type 5 (PDE5) inhibitor therapy. Aim To establish an evidence-based position on ED, including the role erection hardness, potential to improve self-esteem, confidence, and overall sexual relationship satisfaction. Main Outcome Measure The target ED therapy is optimization a rigid response, as assessed by 4-point Erection Hardness Score (EHS). Methods An international panel experts urology, psychology, primary care convened evaluate retrospective data from worldwide phase 2, 3, 4 clinical trials, involving over 10,000 men well recent prospective studies, concerning hardness response PDE5 Results Significant positive correlations were found between EHS Quality Questionnaire International Index Erectile Function (IIEF) function domain score other IIEF measures. also psychosocial measures such satisfaction (assessed Self-Esteem And Relationship questionnaire), medical Dysfunction Inventory Treatment Satisfaction). A shift most frequent 3 (hard enough penetration but not fully hard) at baseline (completely hard rigid) end was accompanied significant improvements intercourse satisfaction, benefits, treatment. Conclusions Support monitoring treating patients their full potential. Quantitative assessment will lead improved outcomes experience optimal Mulhall J, Althof SE, Brock GB, Goldstein I, Junemann K-P, Kirby M. dysfunction: Monitoring practice—Recommendations study panel.