On the likelihood of decompression sickness

摘要: The occurrence of decompression sickness in animals and humans is characterized by the extreme variability individual response. Nevertheless, models analyses results have generally used a critical value approach to separate safe unsafe procedures. Application principle maximum likelihood provides formal consistent way quantify risk apply data on outcome. By use principle, number were fit from dose-response pressure-reduction experiments with both rats men. Several different formulations two- three-parameter described well. In addition summarizing sets, provide maximize experimental observations, test theoretical predictions, estimate uncertainty conclusions, recommend practices.