Acute myeloid leukemia in the elderly.

摘要: The incidence of acute myeloid leukemia (AML) is increasing with age. As the results associated standard intensive chemotherapy remain particularly disappointing in older patients, they represent an ideal target population for clinical and therapeutic investigations. Current attempts are to better define those who may draw a significant benefit from chemotherapy, order test new less approaches remaining patients. Hopefully, lot promising alternative therapies emerging, including hypomethylating agents, histone deacetylase inhibitors, monoclonal antibodies, or chemotherapeutic agents such as cloretazine clofarabine. Reduced-intensity conditioning stem cell transplantation other various immunological another way investigation.