Synthesis of Quinolines through Three-Component Cascade Annulation of Aryl Diazonium Salts, Nitriles, and Alkynes
作者： Hao Wang , Qian Xu , Sheng Shen , Shouyun Yu
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摘要: An efficient and rapid synthesis of multiply substituted quinolines is described. This method enabled by a three-component cascade annulation readily available aryl diazonium salts, nitriles, alkynes. reaction catalyst- additive-free. Various alkynes can participate in this transformation, the yields are up to 83%.
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