Metabolism, mechanism of action and sensitivity profile of fluorocyclopentenylcytosine (RX-3117; TV-1360)
作者： Godefridus J. Peters , Kees Smid , Leonardo Vecchi , Ietje Kathmann , Dzjemma Sarkisjan
DOI: 10.1007/S10637-013-0025-X
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摘要: … Since many cytidine analogs are substrates for cytidine deaminase (CDA) we investigated whether CDA would deaminate RX-3117. For that purpose we added the CDA inhibitor THU …
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