Effects of Molecularly Targeting Hypoxia in Oncology
作者： Giammaria Fiorentini , Camillo Aliberti , Giorgio Benea , Francesco Montagnani , Andrea Mambrini
DOI: 10.1007/978-1-4020-9576-4_7
关键词:
摘要: Abstract The interaction between neoplastic cells and vasculature results in low oxygen tension, extra-cellular pH high interstitial fluid pressure. New multi-target tyrosine kinase inhibitors are new therapeutically options solid tumours. They share the capacity of modulate hypoxia inducible factor (HIF)-VEGF-VEGF receptor sequence that plays a predominant role development
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