Skeletal Changes Following Irradiation of Childhood Tumors

作者: HAROLD KATZMAN , THEODORE WAUGH , WALTER BERDON

DOI: 10.2106/00004623-196951050-00001

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摘要: Skeletal aberrations may develop in patients who survive childhood tumors treated with radiotherapy. In our series of fifty-one children Wilms' tumor and forty-six neuroblastoma, nineteen thirteen, respectively, survived after surgical radiation therapy. Of these, twenty-eight were available for critical follow-up study three to twenty-four years treatment. addition, other retinoblastoma, a hemangiolymphangioma the lower extremity, hemangioma wrist, are included this because interesting skeletal changes following irradiation. The sequelae observed vertebral bodies, scoliosis, hypoplasia ilium rib cage, osteocartilaginous exostoses, epiphyseal destruction limb-length discrepancy deformity, postirradiation sarcoma. These complications radiotherapy related age patient, nature primary disease, amount quality administered. Because such changes, it is belief that all should be followed carefully during their growth. Finally, must re-emphasized these injurious effects not obscure significant role played survival patients.

参考文章(1)
Francis D. Murphy, Walter P. Blount, Cartilaginous Exostoses Following Irradiation Journal of Bone and Joint Surgery, American Volume. ,vol. 44, pp. 662- 668 ,(1962) , 10.2106/00004623-196244040-00006