ACG, the initiator codon for a Sendai virus protein.
作者： K C Gupta , S Patwardhan
DOI: 10.1016/S0021-9258(18)68338-3
关键词:
摘要: Deletion and site-directed point mutants of the polycistronic P/C mRNA Sendai virus revealed that one nonstructural proteins this virus, C' protein, initiates from an ACG codon. This codon occurs in optimum sequence context precedes first AUG mRNA. The results presented communication are consistent with concept ribosomes scan to initiate several its different initiator codons. arrangement weak codons tandem mRNA, i.e. non-AUG suboptimum context, may represent alternate means regulate gene expression eukaryotes their viruses.
sci-hub.st 参考文章(22)
Ellson Y. Chen, Peter H. Seeburg, Supercoil sequencing: a fast method for sequencing plasmid DNA DNA. ,vol. 4, pp. 165- 170 ,(1985)
D S Peabody, Translation initiation at an ACG triplet in mammalian cells. Journal of Biological Chemistry. ,vol. 262, pp. 11847- 11851 ,(1987) , 10.1016/S0021-9258(18)60891-9
S Patwardhan, K C Gupta, Translation initiation potential of the 5' proximal AUGs of the polycistronic P/C mRNA of Sendai virus. A multipurpose vector for site-specific mutagenesis. Journal of Biological Chemistry. ,vol. 263, pp. 4907- 4913 ,(1988) , 10.1016/S0021-9258(18)68872-6
David B . Teplow, Ruedi H. Aebersold, Leroy E . Hood, Stephen B . H. Kent, Electroblotting onto activated glass. High efficiency preparation of proteins from analytical sodium dodecyl sulfate-polyacrylamide gels for direct sequence analysis Journal of Biological Chemistry. ,vol. 261, pp. 4229- 4238 ,(1986) , 10.1016/S0021-9258(17)35652-1
K C Gupta, Antisense oligodeoxynucleotides provide insight into mechanism of translation initiation of two Sendai virus mRNAs. Journal of Biological Chemistry. ,vol. 262, pp. 7492- 7496 ,(1987) , 10.1016/S0021-9258(18)47593-X
R S Zitomer, D A Walthall, B C Rymond, C P Hollenberg, Saccharomyces cerevisiae ribosomes recognize non-AUG initiation codons. Molecular and Cellular Biology. ,vol. 4, pp. 1191- 1197 ,(1984) , 10.1128/MCB.4.7.1191
J A Curran, C Richardson, D Kolakofsky, Ribosomal initiation at alternate AUGs on the Sendai virus P/C mRNA. Journal of Virology. ,vol. 57, pp. 684- 687 ,(1986) , 10.1128/JVI.57.2.684-687.1986
Marilyn Kozak, Selection of initiation sites by eucaryotic ribosomes: effect of inserting AUG triplets upstream from the coding sequence for preproinsulin Nucleic Acids Research. ,vol. 12, pp. 3873- 3893 ,(1984) , 10.1093/NAR/12.9.3873
Polly R. Etkind, Rise K. Cross, Robert A. Lamb, David C. Merz, Purnell W. Choppin, In vitro synthesis of structural and nonstructural proteins of Sendai and SV5 viruses Virology. ,vol. 100, pp. 22- 33 ,(1980) , 10.1016/0042-6822(80)90548-6
Colomba Giorgi, Benjamin M. Blumberg, Daniel Kolakofsky, Sendai virus contains overlapping genes expressed from a single mRNA Cell. ,vol. 35, pp. 829- 836 ,(1983) , 10.1016/0092-8674(83)90115-0